Usp29^tm2Jkim
Targeted Allele Detail

Summary

• Symbol: Usp29^tm2Jkim
• Name: ubiquitin specific peptidase 29; targeted mutation 2, Joomyeong Kim
• MGI ID: MGI:6258929
• Gene: Usp29 Location: Chr7:6733577-6970218 bp, + strand Genetic Position: Chr7, 4.04 cM
• Alliance: Usp29^tm2Jkim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:245745
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A loxP site and an FRT site flanked neomycin resistance gene cassette (in the same transcriptional direction as the targeted gene) were inserted into intron 1. A second loxP site was inserted into intron 1 of upstream neighbor Peg3 (with which it shares a bidirectional promoter), in the opposite orientation of the first loxP site, upstream of the Peg3-DMR (differentially methylated region). (J:245745)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp29 Mutation: 117 strains or lines available

References

• Original: J:245745 Kim J, et al., Inversion of the imprinting control region of the Peg3 domain. PLoS One. 2017;12(7):e0181591
• All: 1 reference(s)