Det1^tm2.1Vmd
Targeted Allele Detail

Summary

• Symbol: Det1^tm2.1Vmd
• Name: DET1 partner of COP1 E3 ubiquitin ligase; targeted mutation 2.1, Vishva M Dixit
• MGI ID: MGI:6258682
• Synonyms: Det1^fl
• Gene: Det1 Location: Chr7:78471295-78497011 bp, - strand Genetic Position: Chr7, 44.81 cM, cytoband D2
• Alliance: Det1^tm2.1Vmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242142
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 2 of Det1 was flanked with loxP sites to create a conditional Det1 allele. (J:242142)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Det1 Mutation: 18 strains or lines available

Notes

Generated from gene-targeted C57BL/6 ES cells by Genentech. J:242142

References

• Original: J:242142 Zhang Z, et al., Transcription factor Etv5 is essential for the maintenance of alveolar type II cells. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3903-3908
• All: 1 reference(s)