Cop1^tm3.1Vmd
Targeted Allele Detail

Summary

• Symbol: Cop1^tm3.1Vmd
• Name: COP1, E3 ubiquitin ligase; targeted mutation 3.1, Vishva M Dixit
• MGI ID: MGI:6258676
• Synonyms: Cop1^fh
• Gene: Cop1 Location: Chr1:159059890-159175210 bp, + strand Genetic Position: Chr1, 69.03 cM, cytoband C3
• Alliance: Cop1^tm3.1Vmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242142
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: The Flag.HA epitope tag sequence was inserted right after the start codon of Cop1 to create this allele. A single loxP site remains in intron 1 after cre-mediated recombination. (J:242142)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cop1 Mutation: 42 strains or lines available

Notes

Generated from gene-targeted C57BL/6 ES cells by genOway. J:242142

References

• Original: J:242142 Zhang Z, et al., Transcription factor Etv5 is essential for the maintenance of alveolar type II cells. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3903-3908
• All: 2 reference(s)