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Polr3dem1(IMPC)Tcp
Endonuclease-mediated Allele Detail
Summary
Symbol: Polr3dem1(IMPC)Tcp
Name: polymerase (RNA) III (DNA directed) polypeptide D; endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI ID: MGI:6257695
Gene: Polr3d  Location: Chr14:70676197-70680887 bp, - strand  Genetic Position: Chr14, 36.32 cM, cytoband D1
Alliance: Polr3dem1(IMPC)Tcp page
IMPC: Polr3d gene page
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from project TCPR1163 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AGTAAGTACACTACGAGAAT targeting the 5' side and AGAAGGATGACGTAGGTGCC targeting the 3' side of a critical region.This resulted in a 539-bp deletion from Chr14: 70441033 to 70441571 (GRCm38). (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Polr3d Mutation:  15 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory