Orai3^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Orai3^em1(IMPC)Bay
• Name: ORAI calcium release-activated calcium modulator 3; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257666
• Gene: Orai3 Location: Chr7:127368987-127374322 bp, + strand Genetic Position: Chr7, 69.73 cM
• Alliance: Orai3^em1(IMPC)Bay page
• IMPC: Orai3 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 RNA, 2 guide sequences GGAAATTGGTACCCTTCGATTGG, AAAGGTGTATGCCGCTGATTGGG, and a donor oligo, which resulted in a Conditional Ready allele. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Orai3 Mutation: 17 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)