Bhlhe23^tm1.1Clc
Targeted Allele Detail

Summary

• Symbol: Bhlhe23^tm1.1Clc
• Name: basic helix-loop-helix family, member e23; targeted mutation 1.1, Constance L Cepko
• MGI ID: MGI:6256729
• Gene: Bhlhe23 Location: Chr2:180416174-180418693 bp, - strand Genetic Position: Chr2, 103.34 cM, cytoband H3-H4
• Alliance: Bhlhe23^tm1.1Clc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266628
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette was inserted 1 kb upstream of the gene. A third loxP site was inserted 300 bp distal to the 3' UTR. Cre-mediated recombination removed the selection cassette and coding sequence. (J:266628)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bhlhe23 Mutation: 8 strains or lines available

References

• Original: J:266628 Kim DS, et al., Identification of molecular markers of bipolar cells in the murine retina. J Comp Neurol. 2008 Apr 10;507(5):1795-810
• All: 2 reference(s)