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Targeted Allele Detail
Symbol: Xcl1tm1.2Ksho
Name: chemokine (C motif) ligand 1; targeted mutation 2.1, Tsuneyasu Kaisho
MGI ID: MGI:6220923
Gene: Xcl1  Location: Chr1:164759213-164763091 bp, - strand  Genetic Position: Chr1, 72.26 cM
Alliance: Xcl1tm1.2Ksho page
Germline Transmission:  Earliest citation of germline transmission: J:235786
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the slection cassette and left exons 2 and 3 floxed. Cre-mediated recombination removed exons 2 and 3. (J:235786)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Xcl1 Mutation:  4 strains or lines available
Original:  J:235786 Ohta T, et al., Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis. Sci Rep. 2016 Mar 23;6:23505
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
The Jackson Laboratory