Tg(ELP4-lacZ)HS234ZfVvh
Transgene Detail

Summary

• Symbol: Tg(ELP4-lacZ)HS234ZfVvh
• Name: transgene insertion HS234Zf, Veronica van Heyningen
• MGI ID: MGI:6203097
• Transgene: Tg(ELP4-lacZ)HS234ZfVvh Location: unknown
• Alliance: Tg(ELP4-lacZ)HS234ZfVvh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Reporter)
• Mutation: Insertion
• Mutation details: A 4.5 kb genomic fragment, containing three DNase I hypersensitivity sites in the human familial aniridia breakpoint region, was placed upstream of the Hsp68 promoter driven beta-galactosidase (lacZ) reporter gene and SV40 poly(A) signal sequences. The fragment is located in the last intron of the elongator acetyltransferase complex subunit 4 gene. In this transgene the genomic fragment is inserted in forward (centromere-telomere) direction. (J:265823)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:265823 Kleinjan DA, et al., Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6. Hum Mol Genet. 2001 Sep 15;10(19):2049-59
• All: 1 reference(s)