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Kif21bem1Adiuj
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Kif21bem1Adiuj
Name: kinesin family member 21B; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID: MGI:6202982
Gene: Kif21b  Location: Chr1:136131389-136177998 bp, + strand  Genetic Position: Chr1, 59.61 cM
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
 
Mutation detailsPlasmids encoding a single guide RNA designed to introduce the T82T point mutation, rs7556510 SNP (ACG to ACA), knock-in mutation into the gene and the cas9 nuclease were introduced into the cytoplasm of fertilized eggs with well recognized pronuclei. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kif21b Mutation:  2 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/21/2020
MGI 6.14
The Jackson Laboratory