Ntsr2tm1.1(cre)Giml
Targeted Allele Detail
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Symbol: |
Ntsr2tm1.1(cre)Giml |
Name: |
neurotensin receptor 2; targeted mutation 1.1, Gina M Leinninger |
MGI ID: |
MGI:6202113 |
Synonyms: |
NtsR2deltaNEO-Cre, NtsR2Dev |
Gene: |
Ntsr2 Location: Chr12:16703477-16710223 bp, + strand Genetic Position: Chr12, 7.98 cM
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Alliance: |
Ntsr2tm1.1(cre)Giml page
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Ntsr2tm1.1(cre)Giml expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Ntsr2 (MGI:108018) |
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Mutation details: The targeting vector was generated by inserting an IRES-Cre between the stop codon and the polyadenylation site of the sequence encoding the 3' end of the mouse NtsR2 gene, with an FRT-flanked NEO cassette placed upstream of the IRES-Cre. Correctly recombined ES clones via homologous recombination were expanded, and injected into mouse blastocystes to generate chimeric males. Mice were bred to a FlpO deleter line to remove neo cessette to make constitutive cre expression throughout life.
(J:263745)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ntsr2
(mouse)
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Original: |
J:263745 Woodworth HL, et al., Identification of Neurotensin Receptor Expressing Cells in the Ventral Tegmental Area across the Lifespan. eNeuro. 2018 Jan-Feb;5(1):ENEURO.0191-17.2018 |
All: |
2 reference(s) |
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