Tg(tetO-Ahr)#Wexi
Transgene Detail

Summary

• Symbol: Tg(tetO-Ahr)#Wexi
• Name: transgene insertion, Wen Xie
• MGI ID: MGI:6202061
• Synonyms: TetRE-CA-AhR
• Transgene: Tg(tetO-Ahr)#Wexi Location: unknown
• Alliance: Tg(tetO-Ahr)#Wexi page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Ahr)#Wexi expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ahr (MGI:105043)	inducible; mouse gene

• Mutation details: Sequence for codons 1-287 and 422- 805 was ligated and placed downstream of tetracycline responsive elements (TRE) and a minimal CMV promoter. The gene is followed by SV40 poly(A) signal sequences. The gene is only expressed, in a tetracycline/doxycycline controllable manner, when mice carrying this allele also carry a tTA or rtTA allele. (J:265654)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:265654 Lee JH, et al., A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis. Gastroenterology. 2010 Aug;139(2):653-63
• All: 1 reference(s)