About   Help   FAQ
Slc3a1tm1Jat
Targeted Allele Detail
Nomenclature
Symbol: Slc3a1tm1Jat
Name: solute carrier family 3, member 1; targeted mutation 1, Jay A Tischfield
MGI ID: MGI:6202022
Gene: Slc3a1  Location: Chr17:85028376-85064236 bp, + strand  Genetic Position: Chr17, 55.17 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:254803
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector replaced 5.7 kb of the sequence that includes exon 1 with a 1.7-kb neomycin cassette under the control of a PGK1 promoter. (J:254803)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc3a1 Mutation:  25 strains or lines available
References
Original:  J:254803 Zee T, et al., alpha-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. Nat Med. 2017 Mar;23(3):288-290
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory