Fbxo30^tm1Yliu
Targeted Allele Detail

Summary

• Symbol: Fbxo30^tm1Yliu
• Name: F-box protein 30; targeted mutation 1, Yang Liu
• MGI ID: MGI:6201599
• Gene: Fbxo30 Location: Chr10:11157074-11173796 bp, + strand Genetic Position: Chr10, 3.66 cM, cytoband A2
• Alliance: Fbxo30^tm1Yliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235393
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A GFP/Neo cassette was inserted 3 bp before the ATG of exon 1 and replaced approximately 3.5 kb of the gene sequence, encompassing the entire region of exon 2 and part of intron 2 (1.4 kb). (J:235393)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxo30 Mutation: 46 strains or lines available

References

• Original: J:235393 Liu Y, et al., Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5. Cell Rep. 2016 May 3;15(5):1111-22
• All: 1 reference(s)