Tg(Krt8-GFP,-HBEGF)4214Muth
Transgene Detail

Summary

• Symbol: Tg(Krt8-GFP,-HBEGF)4214Muth
• Name: transgene insertion 4214, Senthil Muthuswamy
• MGI ID: MGI:6201419
• Synonyms: K8.tGPD
• Transgene: Tg(Krt8-GFP,-HBEGF)4214Muth Location: unknown
• Alliance: Tg(Krt8-GFP,-HBEGF)4214Muth page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Krt8-GFP,-HBEGF)4214Muth expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  chimpanzee	HBEGF (735979)

• Mutation details: The transgenic construct was designed with a mouse keratin 8 promoter followed by a rabbit beta-globin intron driving co-expression of both a turbo green fluorescent protein (tGFP) and a suicide gene, chimpanzee diphtheria toxin receptor, separated by a P2A peptide plus a hygromycin selection cassette. The hygromycin cassette has been removed. tGFP is a fast-maturing short half-life turbo green fluorescent protein. (J:264089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:264089 Sonzogni O, et al., Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol. 2018 Jun;16(6):e2004049
• All: 1 reference(s)