Tg(tetO-SLC33A1)#Lpu
Transgene Detail
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Symbol: |
Tg(tetO-SLC33A1)#Lpu |
Name: |
transgene insertion, Luigi Puglielli |
MGI ID: |
MGI:6201208 |
Synonyms: |
pTRE-AT-1 |
Transgene: |
Tg(tetO-SLC33A1)#Lpu Location: unknown
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Alliance: |
Tg(tetO-SLC33A1)#Lpu page
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Transgene Type: |
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Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) |
Inducer: |
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doxycycline/tetracycline |
Mutation: |
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Insertion
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Tg(tetO-SLC33A1)#Lpu expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
SLC33A1 (9197) |
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inducible; human cDNA |
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Mutation details: The construct contains the human cDNA under the control of tetracycline response elements. The exogenous gene will only be expressed, in a tetracycline/doxycycline-inducible manner, if mice carrying this allele also carry a tTA or rtTA allele.
(J:236112)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:236112 Hullinger R, et al., Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation. J Exp Med. 2016 Jun 27;213(7):1267-84 |
All: |
6 reference(s) |
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