Pax9^tm1.1Tlu
Targeted Allele Detail

Summary

• Symbol: Pax9^tm1.1Tlu
• Name: paired box 9; targeted mutation 1.1, Thomas Lufkin
• MGI ID: MGI:6200895
• Synonyms: Pax9^EGFP:Pax9-
• Gene: Pax9 Location: Chr12:56738552-56759607 bp, + strand Genetic Position: Chr12, 24.53 cM
• Alliance: Pax9^tm1.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239547
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An RAKR furin motif sequence to trim the residual 2A peptide from the upstream protein, glycine-serine-glycine (GCG) spacer, foot-and-mouth disease virus 2A peptide (F2A) sequence, EGFP and FRT-flanked neomycin resistance (neo) cassette were inserted three amino acids after the start of exon 2. Flp-mediated recombination removed the selection cassette. (J:239547)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax9 Mutation: 17 strains or lines available

References

• Original: J:239547 Sivakamasundari V, et al., A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development. Biol Open. 2017 Feb 15;6(2):187-199
• All: 1 reference(s)