Myb^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Myb^M1Btlr
• Name: myeloblastosis oncogene; mutation 1, Bruce Beutler
• MGI ID: MGI:6200393
• Synonyms: Huang_river
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 21,152,617 (v38) on chromosome 10, or base pair 8,368 in the GenBank genomic region NC_000076 encoding Myb. The mutation corresponds to residue 612 in the mRNA sequence NM_010848 within exon 5 of 15 total exons. The mutation results in a serine (S) to proline (P) substitution at position 116 (S116P) in the MYB protein. (J:265264)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 54 strains or lines available

References

• Original: J:265264 Zhong X, et al., Mutagenetix entry for Huang_river. MGI Direct Data Submission. 2018
• All: 1 reference(s)