Mrgprgem1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Mrgprgem1(IMPC)J |
Name: |
MAS-related GPR, member G; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6200361 |
Gene: |
Mrgprg Location: Chr7:143317447-143320730 bp, - strand Genetic Position: Chr7, 88.31 cM
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Alliance: |
Mrgprgem1(IMPC)J page
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IMPC: |
Mrgprg gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from project Mrgprg-115062J-8267M was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATAGCCCCCCAAGACCTGAC and TGTTCTCCATATTCAACATC, which resulted in an 819 bp deletion beginning at Chromosome 7 position 143,764,544 bp and ending after 143,765,362 bp (GRCm38/mm10). This mutation deletes 819 bp of ENSMUSE00000378852 (exon 2) and is predicted to cause a deletion of 273 amino acids after residue 4 and before residue 277. This would effectively remove all but 16 amino acids of the coding sequence.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
1 reference(s) |
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