Tcf12^em1Jlr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tcf12^em1Jlr
• Name: transcription factor 12; endonuclease-mediated mutation 1, John L R Rubenstein
• MGI ID: MGI:6200109
• Synonyms: hs623^Tm1, Rr406442^em1Jlr
• Gene: Tcf12 Location: Chr9:71751534-72019611 bp, - strand Genetic Position: Chr9, 39.85 cM
• Alliance: Tcf12^em1Jlr page

Mutation origin

• Strain of Origin: CD-1

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details : CRISPR/Cas9 mediated recombination deleted a 734 bp region (GRCm39:chr9:71882287-71883023) of an enhancer element (hs623 or Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
  • Carrying any Tcf12 Mutation: 75 strains or lines available
• References:
  • Original: J:264806 Sandberg M, et al., Genomic analysis of transcriptional networks directing progression of cell states during MGE development. Neural Dev. 2018 Sep 14;13(1):21
  • All: 1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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