Aicda^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Aicda^m1Btlr
• Name: activation-induced cytidine deaminase; mutation 1, Bruce Beutler
• MGI ID: MGI:6199978
• Synonyms: creeper
• Gene: Aicda Location: Chr6:122530768-122541139 bp, + strand Genetic Position: Chr6, 57.65 cM, cytoband F2
• Alliance: Aicda^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 122,561,867 (v38) on chromosome 6, or base pair 8,059 in the GenBank genomic region NC_000072 encoding Aicda. The mutation corresponds to residue 547 in the mRNA sequence NM_009645 within exon 4 of 5 total exons. The mutation results in a valine to isoleucine substitution at residue 152 (V152I) in the AID protein. (J:265155)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aicda Mutation: 55 strains or lines available

References

• Original: J:265155 Yue T, et al., Mutagenetix entry for creeper. MGI Direct Data Submission. 2018
• All: 1 reference(s)