Cd44^tm1.1Vors
Targeted Allele Detail

Summary

• Symbol: Cd44^tm1.1Vors
• Name: CD44 antigen; targeted mutation 1.1, Veronique Orian-Rousseau
• MGI ID: MGI:6199605
• Synonyms: Cd44^fl
• Gene: Cd44 Location: Chr2:102641486-102732010 bp, - strand Genetic Position: Chr2, 54.13 cM
• Alliance: Cd44^tm1.1Vors page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265119
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was floxed. Cre-mediated recombination removed the floxed neomycin resistance cassette. (J:265119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd44 Mutation: 73 strains or lines available

References

• Original: J:265119 Shatirishvili M, et al., Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016 Nov 10;7(11):e2461
• All: 4 reference(s)