Hr^m6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Hr^m6Btlr
• Name: lysine demethylase and nuclear receptor corepressor; mutation 6, Bruce Beutler
• MGI ID: MGI:6198336
• Synonyms: angie
• Gene: Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
• Alliance: Hr^m6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 70,567,833 (v38) on chromosome 14, or base pair 13,778 in the GenBank genomic region NC_000080 encoding Hr. The mutation corresponds to residue 3,708 in the mRNA sequence NM_021877 within exon 16 of 20 total exons. The mutation results in an aspartic acid to glycine substitution at position 1,005 (D1005G) in the HR protein. (J:264680)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hr Mutation: 84 strains or lines available

References

• Original: J:264680 Roy B, et al., Mutagenetix entry for angie. MGI Direct Data Submission. 2018
• All: 1 reference(s)