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Tyro3m1
Spontaneous Allele Detail
Nomenclature
Symbol: Tyro3m1
Name: TYRO3 protein tyrosine kinase 3; mutation 1
MGI ID: MGI:6197245
Synonyms: Tyro3R7Y
Gene: Tyro3  Location: Chr2:119797740-119818104 bp, + strand  Genetic Position: Chr2, 59.97 cM, cytoband F
Mutation
origin
Strain of Origin:  various
Mutation
description
Allele Type:    Spontaneous (Not Applicable)
Mutation:    Single point mutation
 
Mutation detailsA single C to T transiton in the signal sequence causes an arginine to tryptophan substitution at amino acid 7. (J:241666)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tyro3 Mutation:  11 strains or lines available
References
Original:  J:241666 Kim DY, et al., The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation. Dis Model Mech. 2017 May 01;10(5):581-595
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/16/2019
MGI 6.14
The Jackson Laboratory