Brap^tm1Yfng
Targeted Allele Detail

Summary

• Symbol: Brap^tm1Yfng
• Name: BRCA1 associated protein; targeted mutation 1, Yuanyi Feng
• MGI ID: MGI:6195007
• Synonyms: Brap^flox
• Gene: Brap Location: Chr5:121798626-121825312 bp, + strand Genetic Position: Chr5, 61.9 cM, cytoband F
• Alliance: Brap^tm1Yfng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254235
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP/Frt site flanked neomycin resistance gene cassette was inserted into intron 1 and a third loxP site was inserted into intron 3. This creates a conditional-ready allele with exons 2 and 3 floxed. (J:197131)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brap Mutation: 30 strains or lines available

References

• Original: J:197131 Lanctot AA, et al., Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
• All: 4 reference(s)