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Adam18tm1Osb
Targeted Allele Detail
Nomenclature
Symbol: Adam18tm1Osb
Name: a disintegrin and metallopeptidase domain 18; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:6194894
Gene: Adam18  Location: Chr8:24602246-24674755 bp, - strand  Genetic Position: Chr8, 12.82 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234235
Parent Cell Line:  G101 (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 4 was replaced with an FRT and loxP flanked neo cassette in inverse orientation. (J:234235)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adam18 Mutation:  42 strains or lines available
References
Original:  J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory