Gt(ROSA)26Sor^{tm1(CAG-tdTomato)Mabe}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-tdTomato)Mabe}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Manabu Abe
• MGI ID: MGI:6192640
• Synonyms: CAG-floxed STOP tdTomato
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-tdTomato)Mabe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263738
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A vector inserted into the locus was designed with (from 5' to 3') a 5' homology arm, CAG promoter, loxP-flanked neomycin and stop cassette, tdTomato gene and a 3' homology arm. (J:263738)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1062 strains or lines available

References

• Original: J:263738 Nakayama H, et al., Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum. Nat Commun. 2018 Jul 19;9(1):2830
• All: 3 reference(s)