Triobp^tm1Sik
Targeted Allele Detail

Summary

• Symbol: Triobp^tm1Sik
• Name: TRIO and F-actin binding protein; targeted mutation 1, Shin-ichiro Kitajiri
• MGI ID: MGI:6189198
• Synonyms: Triobp^deltaEx9-10
• Gene: Triobp Location: Chr15:78831924-78890069 bp, + strand Genetic Position: Chr15, 37.7 cM
• Alliance: Triobp^tm1Sik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290568
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Modified isoform(s), Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ reporter gene with a nuclear localization sequence and a floxed neomycin resistance cassette replaced exons 9 and 10. (J:290568)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Triobp Mutation: 74 strains or lines available

References

• Original: J:290568 Katsuno T, et al., TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing. JCI Insight. 2019 Jun 20;4(12)
• All: 3 reference(s)