Dp(19Rln1-Gldc)2Uru
Targeted Allele Detail

Summary

• Symbol: Dp(19Rln1-Gldc)2Uru
• Name: duplication, Chr 19, Uwe Rudolph 2
• MGI ID: MGI:6189110
• Gene: Dp(19Rln1-Gldc)2Uru Location: unknown Genetic Position: Chr19, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Duplication
• Dp(19Rln1-Gldc)2Uru involves 25 genes/genome features (Rln1, Gm52390, Plgrkt ...) View all
• Mutation details: The donor constructed mice with a 0.9-Mb deletion on mouse chromosome 19 syntenic with the human 9p24.1 region by trans-allelic recombination in vivo. The deletion includes the genes Rln1, Plgrkt, Cd274, Pdcd1lg2, Ric1, Ermp1, Mlana, 9930021J03Rik, Ranbp6, Il33, Trpd52l3, Uhrf2, and Gldc. Briefly, the donor inserted loxP sites into the mouse genome by targeting sites to flank the region to duplicate or delete. Cre-mediated recombination duplicated the intervening sequence. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dp(19Rln1-Gldc)2Uru Mutation: 0 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)