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Coro2bem1(IMPC)J
Endonuclease-mediated Allele Detail
Summary
Symbol: Coro2bem1(IMPC)J
Name: coronin, actin binding protein, 2B; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6188963
Gene: Coro2b  Location: Chr9:62326774-62444326 bp, - strand  Genetic Position: Chr9, 33.71 cM
Alliance: Coro2bem1(IMPC)J page
IMPC: Coro2b gene page
Mutation
origin
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 4 guide sequences GCCACAGTCAGCAGGCAGAT, AGAGAAGCAACGAGAGTAGA, GGACCCACACGTGCCACCTT and TGGTAGCTCTACTAGGGGCA, which resulted in a 358 bp deletion beginning at Chromosome 9 position 62,427,786 bp and ending after 62,428,143 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001375364 (exon 8) and 261 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 290 and early truncation 21 amino acids later. (J:188991)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Coro2b Mutation:  69 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory