Zfp36^tm1.1Pkov
Targeted Allele Detail

Summary

• Symbol: Zfp36^tm1.1Pkov
• Name: zinc finger protein 36; targeted mutation 1.1, Pavel Kovarik
• MGI ID: MGI:6163998
• Synonyms: TTP^fl
• Gene: Zfp36 Location: Chr7:28076208-28078680 bp, - strand Genetic Position: Chr7, 16.72 cM
• Alliance: Zfp36^tm1.1Pkov page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262526
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites and a neomycin cassette and a third loxP site were inserted downstream of the floxed exon 2. The selection cassette was excised by transiently transfecting ES cells with a cre recombinase-expressing construct. (J:262526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp36 Mutation: 17 strains or lines available

References

• Original: J:262526 Kratochvill F, et al., Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. Mol Syst Biol. 2011 Dec 20;7:560
• All: 2 reference(s)