Agtpbp1^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Agtpbp1^tm1.1Ics
• Name: ATP/GTP binding protein 1; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:6161787
• Synonyms: Ccp1^lox
• Gene: Agtpbp1 Location: Chr13:59597348-59705184 bp, - strand
• Alliance: Agtpbp1^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259182
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP was inserted upstream of exon 20, and an FRT site, loxP site, neomycin cassette, FRT site, and loxP site were inserted downstream of exon 21. FLP-mediated recombination removed the neomycin cassette, leaving exons 20-21 floxed. (J:259182)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agtpbp1 Mutation: 66 strains or lines available

References

• Original: J:259182 Silva CG, et al., Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Cell. 2018 Feb 22;172(5):1063-1078.e19
• All: 4 reference(s)