Gt(ROSA)26Sor^{tm3(Tlr4,-GFP)Gbrt}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm3(Tlr4,-GFP)Gbrt}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Greg Barton
• MGI ID: MGI:6160900
• Synonyms: R26-TLR4
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm3(Tlr4,-GFP)Gbrt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm3(Tlr4,-GFP)Gbrt} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tlr4 (MGI:96824)

• Mutation details: The targeting vector contains a loxP-flanked STOP cassette, including a neomycin resistance (neo) cassette, upstream of the toll-like receptor 4 (Tlr4) gene. An internal ribosome entry site (IRES) fused to an enhanced green fluorescent protein (EGFP) sequence was inserted at the 3' end of Tlr4. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1060 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)