Slurp2^tm1Sgy
Targeted Allele Detail

Summary

• Symbol: Slurp2^tm1Sgy
• Name: secreted Ly6/Plaur domain containing 2; targeted mutation 1, Stephen G Young
• MGI ID: MGI:6159740
• Synonyms: Slurp2X^-
• Gene: Slurp2 Location: Chr15:74614688-74618536 bp, - strand Genetic Position: Chr15, 34.27 cM
• Alliance: Slurp2^tm1Sgy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231067
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A nonsense mutation, changing leucine codon 27 into a stop codon, was introduced into exon 2. A loxP site flanked neomycin resistance gene cassette was inserted downstream of terminal exon 3. (J:231067)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slurp2 Mutation: 11 strains or lines available

References

• Original: J:231067 Allan CM, et al., Palmoplantar Keratoderma in Slurp2-Deficient Mice. J Invest Dermatol. 2016 Feb;136(2):436-43
• All: 1 reference(s)