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Uxttm1.2Sklo
Targeted Allele Detail
Summary
Symbol: Uxttm1.2Sklo
Name: ubiquitously expressed prefoldin like chaperone; targeted mutation 1.2, Susan K Logan
MGI ID: MGI:6159373
Gene: Uxt  Location: ChrX:20818162-20828259 bp, - strand  Genetic Position: ChrX, 16.46 cM, cytoband A2
Alliance: Uxttm1.2Sklo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:261955
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site and FTR flanked inverted pgk-neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 3. (J:261955)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Uxt Mutation:  4 strains or lines available
References
Original:  J:261955 Schafler ED, et al., UXT is required for spermatogenesis in mice. PLoS One. 2018;13(4):e0195747
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory