Uxt^tm1.1Sklo
Targeted Allele Detail

Summary

• Symbol: Uxt^tm1.1Sklo
• Name: ubiquitously expressed prefoldin like chaperone; targeted mutation 1.1, Susan K Logan
• MGI ID: MGI:6159372
• Synonyms: Uxt^F, Uxt^Flox
• Gene: Uxt Location: ChrX:20818162-20828259 bp, - strand Genetic Position: ChrX, 16.46 cM, cytoband A2
• Alliance: Uxt^tm1.1Sklo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261955
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FTR flanked inverted pgk-neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:261955)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uxt Mutation: 4 strains or lines available

References

• Original: J:261955 Schafler ED, et al., UXT is required for spermatogenesis in mice. PLoS One. 2018;13(4):e0195747
• All: 2 reference(s)