Mtor^em1Mfz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mtor^em1Mfz
• Name: mechanistic target of rapamycin kinase; endonuclease-mediated mutation 1, Mike Fainzilber
• MGI ID: MGI:6158356
• Synonyms: mTOR 3'UTR^-
• Gene: Mtor Location: Chr4:148533068-148642140 bp, + strand Genetic Position: Chr4, 78.76 cM, cytoband E1
• Alliance: Mtor^em1Mfz page

Mutation origin

• Strain of Origin: (BALB/c x C57BL/6)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Undefined
• CRISPR targeting removed the 3' UTR. (J:261780)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtor Mutation: 117 strains or lines available

References

• Original: J:261780 Terenzio M, et al., Locally translated mTOR controls axonal local translation in nerve injury. Science. 2018 Mar 23;359(6382):1416-1421
• All: 2 reference(s)