S100a10^tm1Kah
Targeted Allele Detail

Summary

• Symbol: S100a10^tm1Kah
• Name: S100 calcium binding protein A10 (calpactin); targeted mutation 1, Katherine A Hajjar
• MGI ID: MGI:6157521
• Gene: S100a10 Location: Chr3:93462424-93471952 bp, + strand Genetic Position: Chr3, 40.51 cM, cytoband F1-F2
• Alliance: S100a10^tm1Kah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244820
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A EGFP/neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expressin in lung. (J:244820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any S100a10 Mutation: 34 strains or lines available

References

• Original: J:244820 Luo M, et al., Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. J Exp Med. 2017 Sep 04;214(9):2535-2545
• All: 1 reference(s)