Gpr119^tm1Tjkw
Targeted Allele Detail

Summary

• Symbol: Gpr119^tm1Tjkw
• Name: G-protein coupled receptor 119; targeted mutation 1, Timothy J Kowalski
• MGI ID: MGI:6157471
• Gene: Gpr119 Location: ChrX:47756856-47763355 bp, - strand Genetic Position: ChrX, 25.69 cM
• Alliance: Gpr119^tm1Tjkw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244912
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced most of the coding region. (J:244912)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr119 Mutation: 7 strains or lines available

References

• Original: J:244912 Lan H, et al., GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis. J Endocrinol. 2009 May;201(2):219-30
• All: 1 reference(s)