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Spontaneous Allele Detail
Symbol: Ogg1m2
Name: 8-oxoguanine DNA-glycosylase 1; mutation 2
MGI ID: MGI:6157074
Synonyms: OGG1-R304W
Gene: Ogg1  Location: Chr6:113326972-113334877 bp, + strand  Genetic Position: Chr6, 52.75 cM, cytoband E-F1
Strain of Origin:  various
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Single point mutation
Mutation detailsA cytosine to thymine change at the twelfth nucleotide in exon 6 results in a substitution of the 304th amino acid, arginine, by tryptophan (R304W). (J:59724)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ogg1 Mutation:  20 strains or lines available
Original:  J:59724 Choi JY, et al., Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation. Free Radic Biol Med. 1999 Oct;27(7-8):848-54
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory