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Brwd1em1(IMPC)Tcp
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Brwd1em1(IMPC)Tcp
Name: bromodomain and WD repeat domain containing 1; endonuclease mediated mutation 1, Toronto Centre for Phenogenomics
MGI ID: MGI:6156470
Gene: Brwd1  Location: Chr16:95992092-96082526 bp, - strand  Genetic Position: Chr16, 56.77 cM
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Toronto Centre for Phenogenomics by injecting CAS9 RNA and 4 guide sequences CCGGGCAGGGGACGCGCGGCCGT, AAGACAGGGACGGTCAGCGGCGG, CCCGTCGCCCCGGGACGCCGGAC, ACCCCGCCACCGCGAGCCCTCGG, which resulted in a Exon Deletion. (J:237616)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Brwd1 Mutation:  21 strains or lines available
References
Original:  J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory