Ilrun^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ilrun^em1(IMPC)Tcp
• Name: inflammation and lipid regulator with UBA-like and NBR1-like domains; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6156447
• Gene: Ilrun Location: Chr17:27970206-28039516 bp, - strand Genetic Position: Chr17, 14.59 cM
• Alliance: Ilrun^em1(IMPC)Tcp page
• IMPC: Ilrun gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Centre for Phenogenomics using Cas9 and guides with spacer sequences ATTCTGGTAAGTGTATAACG, CCTAAGAAAGGATTTCCCTC, CGTCACTACTGAGAAACTAC, and GACTCAGTCACACCAGGTGG that targeted exon(s) ENSMUSE00000449145.2. This resulted in deletion(s) of 314 bp (location: Chr17:28012864-28013177; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ilrun Mutation: 91 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)