Enkur^tm1Hmf
Targeted Allele Detail

Summary

• Symbol: Enkur^tm1Hmf
• Name: enkurin, TRPC channel interacting protein; targeted mutation 1, Harvey M Florman
• MGI ID: MGI:6156078
• Synonyms: Enkur^tm
• Gene: Enkur Location: Chr2:21185542-21210176 bp, - strand Genetic Position: Chr2, 14.82 cM
• Alliance: Enkur^tm1Hmf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253966
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neomycin resistance cassette. Immunofluorescence confirmed the absence of protein expression in the trachea. (J:253966)

Expression

In Mice Carrying this Mutation:	19 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enkur Mutation: 15 strains or lines available

References

• Original: J:253966 Sigg MA, et al., Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev Cell. 2017 Dec 18;43(6):744-762.e11
• All: 2 reference(s)