Gt(ROSA)26Sor^{tm1(Bach2)Kuro}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Bach2)Kuro}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Tomohiro Kurosaki
• MGI ID: MGI:6154979
• Synonyms: Bach2 TG, Gt(ROSA)26Sor^{tm1(Bach2,EGFP)Kuro}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Bach2)Kuro} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241902
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Bach2)Kuro} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Bach2

• Mutation details: A construct containing a loxP site, STOP cassette, loxP site, Flag-tagged Bach2 cDNA, FRT site, IRES, EGFP, and FRT site was targeted to the locus. This creates a conditional-ready allele that will only be expressed after cre-mediated deletion of the STOP cassette. (J:241902)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:241902 Kuwahara M, et al., Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop. Nat Commun. 2016 Sep 01;7:12596
• All: 2 reference(s)