Lhfpl4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Lhfpl4^tm1Lex
• Name: lipoma HMGIC fusion partner-like protein 4; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:6154882
• Synonyms: Lhfpl4^-
• Gene: Lhfpl4 Location: Chr6:113145051-113172345 bp, - strand Genetic Position: Chr6, 52.74 cM
• Alliance: Lhfpl4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254795
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 (the latter containing the ATG translation start site) and intervening intron 1, were replaced with sequence containing a lacZ reporter cassette and a LoxP site flanked puromycin resistance gene cassette. (J:254795)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lhfpl4 Mutation: 11 strains or lines available

Notes

Taconic mouse line TF4076.

References

• Original: J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
• All: 1 reference(s)