Git1^tm1.1Jpan
Targeted Allele Detail

Summary

• Symbol: Git1^tm1.1Jpan
• Name: GIT ArfGAP 1; targeted mutation 1.1, Jinjiang Pang
• MGI ID: MGI:6154880
• Synonyms: Git1^f
• Gene: Git1 Location: Chr11:77384388-77398612 bp, + strand Genetic Position: Chr11, 46.61 cM
• Alliance: Git1^tm1.1Jpan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241676
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 to 7 were flanked by loxP sites and a FRT-flanked neomycin phosphotransferase cassette was inserted after exon 7 and before the second loxP site. Flp-mediated recombination removed the selection cassette, leaving exons 3-7 floxed. (J:241676)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Git1 Mutation: 43 strains or lines available

References

• Original: J:241676 Majumder S, et al., G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling. Cell Rep. 2016 Dec 06;17(10):2532-2541
• All: 1 reference(s)