Gt(ROSA)26Sor^{tm1(CAG-Fto,-GFP)Sbq}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Fto,-GFP)Sbq}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Shu-Bing Qian
• MGI ID: MGI:6154621
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Fto,-GFP)Sbq} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260810
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Fto,-GFP)Sbq} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Fto

• Mutation details: A CAG promoter, floxed stop cassette, Fto cDNA with a fused myc tag and FRT flanked IRES-GFP cassette were inserted upstream of exon 1 via homologous recombination. (J:260810)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1083 strains or lines available

References

• Original: J:260810 Zhou J, et al., N(6)-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response. Mol Cell. 2018 Feb 15;69(4):636-647.e7
• All: 1 reference(s)