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Lta4hem2(IMPC)Wtsi
Endonuclease-mediated Allele Detail
Summary
Symbol: Lta4hem2(IMPC)Wtsi
Name: leukotriene A4 hydrolase; endonuclease-mediated mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:6153769
Gene: Lta4h  Location: Chr10:93289273-93320737 bp, + strand  Genetic Position: Chr10, 48.42 cM, cytoband C3
Alliance: Lta4hem2(IMPC)Wtsi page
IMPC: Lta4h gene page
Mutation
origin
Strain of Origin:  C57BL/6N
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsThis allele from IMPC was generated at Welcome Trust Sanger Institute by injecting CAS9 RNA, the guide sequence CACATGAAATATCTCATAGCTGG, and a donor oligo, which resulted in a Point Mutation allele. (J:237616)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lta4h Mutation:  28 strains or lines available
References
Original:  J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory