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Nr0b1em2(IMPC)Wtsi
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Nr0b1em2(IMPC)Wtsi
Name: nuclear receptor subfamily 0, group B, member 1; endonuclease mediated mutation 2, Wellcome Trust Sanger Insititute
MGI ID: MGI:6153726
Gene: Nr0b1  Location: ChrX:85235381-85239553 bp, + strand  Genetic Position: ChrX, 39.67 cM
Mutation
origin
Strain of Origin:  C57BL/6N
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Welcome Trust Sanger Institute by injecting CAS9 RNA and 4 guide sequences CCCTTTGAGCTTTCGAGGTCATG, CTGCGCCCTTGTCCAAGAGGAGG, ATCAGGAATACCCTGTCAAGTGG, CCAGAAACTTGGCACTGGATTGG, which resulted in a Exon Deletion. (J:237616)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr0b1 Mutation:  9 strains or lines available
References
Original:  J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory