Pgam5^tm1Hijo
Targeted Allele Detail

Summary

• Symbol: Pgam5^tm1Hijo
• Name: phosphoglycerate mutase family member 5; targeted mutation 1, Hidenori Ichijo
• MGI ID: MGI:6151134
• Gene: Pgam5 Location: Chr5:110407001-110417765 bp, - strand Genetic Position: Chr5, 53.43 cM, cytoband F
• Alliance: Pgam5^tm1Hijo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260429
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 4.9-kb fragment of the Pgam5 gene, containing exons 15, was replaced by a reversed-oriented neomycin phosphotransferase cassette. (J:260429)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pgam5 Mutation: 25 strains or lines available

References

• Original: J:260429 Sekine S, et al., The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress. EBioMedicine. 2016 Mar;5:82-92
• All: 2 reference(s)