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Shmt2em1Jiha
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Shmt2em1Jiha
Name: serine hydroxymethyltransferase 2 (mitochondrial); endonuclease mediated mutation 1, Jun-Ichi Hayashi
MGI ID: MGI:6150909
Synonyms: Shmt2 m
Gene: Shmt2  Location: Chr10:127517123-127522444 bp, - strand  Genetic Position: Chr10, 74.51 cM
Mutation
origin
Strain of Origin:  C57BL/6JJcl
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
    CRISPR mutagenesis induced an insertion of a single T in the gene, resulting in a frame shift. (J:259713)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shmt2 Mutation:  11 strains or lines available
References
Original:  J:259713 Tani H, et al., Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal. Sci Rep. 2018 Jan 11;8(1):425
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory